Who acts Karen mother? What actress takes on the role of Karen Wheeler in the series? Whom is the performer behind Karen Wheeler? Karen is brought to life by which actress? Who acts as the character of Karen the mother on the series? Who is the talent personifying Karen Wheeler's character to life? What actress takes on the role of Karen Mrs. Wheeler in the television show? Who acts Karen Mrs. Wheeler? Who is the talented individual portraying Karen the mother on the show? Which actress brings the character of Karen Wheeler to the screen?