Whom plays Mrs. Wheeler Wheeler? Which actor embodies the role of Karen Wheeler in the show? Who is the performer behind Karen Wheeler? Karen is brought to life by what actor? Who plays the character of Karen Wheeler on the series? Who is the talent showcasing Karen the mother's character to life? What actor takes on the role of Karen Mrs. Wheeler in the series? Whoever acts Karen Wheeler? Who is the talented individual enacting Karen the mother on the show? Which actress incarnates the character of Karen Wheeler to the screen?